{"id":1226,"date":"2024-09-19T13:29:08","date_gmt":"2024-09-19T13:29:08","guid":{"rendered":"https:\/\/www.microplanet.at\/?page_id=1226"},"modified":"2025-11-27T13:02:32","modified_gmt":"2025-11-27T12:02:32","slug":"project-3","status":"publish","type":"page","link":"https:\/\/www.microplanet.at\/index.php\/project-3\/","title":{"rendered":"Project 3"},"content":{"rendered":"\n
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Project 3<\/h2>\n\n\n\n

Chemical Perturbations and Microbiome Functioning<\/strong><\/h2>\n\n\n\n

Anthropogenic chemicals play a major role in the perturbation of microbiomes. However, our knowledge about the impact of these widespread, almost ubiquitous pollutants on microbiome function and host interactions is surprisingly incomplete because until recently, no adequate tools for directly tackling this important research were available. In project 3, we will focus on two major groups of anthropogenic chemicals: pharmaceuticals and tire wear particles.<\/p>\n\n\n\n

We will study how the most commonly used pharmaceuticals in Austria affect the composition and function of human gut microbiomes and how these chemical microbiome perturbations are linked to treatment side effects such as the development and spread of antimicrobial resistance, and therapy efficiency. Furthermore, we will pave the way for understanding biotransformation of these pharmaceuticals, which perturb human gut, sewer, and wastewater treatment microbiomes.<\/p>\n\n\n\n

We will also investigate perturbations by microplastics and toxic additives of tire wear particles in-situ <\/em>from soil and sediment to host- associated (human, plants, and animals) microbiomes. We aim to significantly improve our understanding of microbiome perturbation by emerging pollutants across systems. These insights will also serve as a strong basis for targeted microbiome manipulation strategies.<\/p>\n<\/div>\n<\/div>\n\n\n\n

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Involved KEY RESEARCHERs<\/h3>\n\n\n\n
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michael wagner<\/p>\n\n\n\n

Project Leader<\/p>\n\n\n\n

UNIVERSITY of vienna<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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david berry<\/p>\n\n\n\n

Project Member<\/p>\n\n\n\n

university of vienna<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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ruth birner-gr\u00fcnberger<\/p>\n\n\n\n

Project Member<\/p>\n\n\n\n

technische universit\u00e4t wien (tu wien)<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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thomas b\u00f6ttcher<\/p>\n\n\n\n

Project Member<\/p>\n\n\n\n

university of vienna<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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Kristina djinovic-carugo<\/p>\n\n\n\n

Project Member<\/p>\n\n\n\n

UNIVERSITY of vienna<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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peter ertl<\/p>\n\n\n\n

Project Member<\/p>\n\n\n\n

technische universit\u00e4t wien (tu wien)<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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thilo hofmann<\/p>\n\n\n\n

Project Member<\/p>\n\n\n\n

university of vienna<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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katharina kitzinger<\/p>\n\n\n\n

Project Member<\/p>\n\n\n\n

UNIVERSITY of vienna<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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alexander loy<\/p>\n\n\n\n

Project Member<\/p>\n\n\n\n

UNIVERSITY of vienna<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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christine moissl-eichinger<\/p>\n\n\n\n

Project Member<\/p>\n\n\n\n

medical university of graz<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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alexander moschen<\/p>\n\n\n\n

Project Member<\/p>\n\n\n\n

johannes kepler university linz<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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jillian petersen<\/p>\n\n\n\n

Project Member<\/p>\n\n\n\n

UNIVERSITY of Vienna<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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andreas richter<\/p>\n\n\n\n

Project Member<\/p>\n\n\n\n

UNIVERSITY of Vienna<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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leonid sazanov<\/p>\n\n\n\n

Project Member<\/p>\n\n\n\n

institute of science and technology austria<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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angela sessitsch<\/p>\n\n\n\n

Project Member<\/p>\n\n\n\n

austrian institute of technology<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n

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michael zumstein<\/p>\n\n\n\n

Project Member<\/p>\n\n\n\n

UNIVERSITY of Vienna<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n\n\n\n

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InVolved institutions<\/h2>\n<\/div>\n\n\n\n
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work packages in project 3<\/h2>\n<\/div>\n\n\n\n
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Work package 3.1<\/h3>\n\n\n\n

Impact of Drugs on Microbiomes in Humans and Wastewater Treatment <\/strong><\/p>\n\n\n\n

Human gut and wastewater microbiomes interact with human-targeted and antibiotic drugs in multiple ways, which can have profound consequences for the treatment of patients and the health of ecosystems that receive drugs. The results of Work Package 3.1 will substantially improve our understanding of drug-microbiome interactions and reveal the in-situ <\/em>landscape of drug inhibition\/stimulation in drug-affected systems.<\/p>\n\n\n\n

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More \u2192<\/strong><\/a><\/p>\n<\/div>\n<\/div>\n\n\n\n

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Work package 3.2<\/h3>\n\n\n\n

Impact of Emerging Pollutants on Microbiomes across Systems <\/strong><\/p>\n\n\n\n

Chemical pollution can have profound effects on microbial communities, and thus on biodiversity, ecosystem, and human health. Work Package 3.2 aims to understand how tire wear particles, a substantial, but still underestimated source of microplastics, and their additives affect microbiome composition and functions in soils, plants, animals and human tissues.<\/p>\n\n\n\n

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More \u2192<\/strong><\/a><\/p>\n<\/div>\n<\/div>\n\n\n\n

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Read more on Project 1<\/a><\/div>\n\n\n\n
Read more on Project 2<\/a><\/div>\n\n\n\n
Read more on Project 4<\/a><\/div>\n\n\n\n
Read more on Project 5<\/a><\/div>\n\n\n\n
Read more on Project 6<\/a><\/div>\n\n\n\n
Read more on Project 7<\/a><\/div>\n<\/div>\n<\/section>\n<\/div>\n\n\n\n
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Find us on social media<\/p>\n\n\n\n

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\"LinkedIn\"<\/a><\/figure>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/section>\n","protected":false},"excerpt":{"rendered":"

Project 3 Chemical Perturbations and Microbiome Functioning Anthropogenic chemicals play a major role in the perturbation of microbiomes. However, our knowledge about the impact of these widespread, almost ubiquitous pollutants on microbiome function and host interactions is surprisingly incomplete because until recently, no adequate tools for directly tackling this important research were available. In project […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1226","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/pages\/1226","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/comments?post=1226"}],"version-history":[{"count":17,"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/pages\/1226\/revisions"}],"predecessor-version":[{"id":6427,"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/pages\/1226\/revisions\/6427"}],"wp:attachment":[{"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/media?parent=1226"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}