{"id":4762,"date":"2025-04-25T08:34:52","date_gmt":"2025-04-25T07:34:52","guid":{"rendered":"https:\/\/www.microplanet.at\/?p=4762"},"modified":"2025-04-25T08:34:52","modified_gmt":"2025-04-25T07:34:52","slug":"new-coe-publication-identifies-novel-archaea-species-in-human-gut","status":"publish","type":"post","link":"https:\/\/www.microplanet.at\/index.php\/news\/new-coe-publication-identifies-novel-archaea-species-in-human-gut\/","title":{"rendered":"New CoE Publication identifies novel Archaea species in human gut"},"content":{"rendered":"\n<figure class=\"wp-block-image size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"586\" height=\"445\" src=\"https:\/\/www.microplanet.at\/wp-content\/uploads\/2025\/04\/Methanobrevibacter.png\" alt=\"\" class=\"wp-image-4777\" style=\"width:620px;height:auto\" srcset=\"https:\/\/www.microplanet.at\/wp-content\/uploads\/2025\/04\/Methanobrevibacter.png 586w, https:\/\/www.microplanet.at\/wp-content\/uploads\/2025\/04\/Methanobrevibacter-300x228.png 300w\" sizes=\"auto, (max-width: 586px) 100vw, 586px\" \/><\/figure>\n\n\n\n<p class=\"has-small-font-size\" style=\"font-style:normal;font-weight:300\">Scanning electron micrograph of <em>Methanobrevibacter smithii<\/em>, <em>Methanobrevibacter smithii<\/em> GRAZ-2, and<em> Methanobrevibacter intestini<\/em> WWM1085.<\/p>\n\n\n\n<p>CoE Deputy Director of Research Christine Moissl-Eichinger and her team at the Medical University of Graz have identified a previously unknown methane-producing Archaea species from the human intestine.<\/p>\n\n\n\n<p>Collaborating with colleagues from the Deutsche Sammlung von Mikroorganismen und Zellkulturen (DSMZ, Germany) and the University of Illinois (USA), they employed the latest techniques, such as targeted anaerobic cultivation, high-resolution electron microscopy, and comprehensive genome sequencing, to isolate two Methanobrevibacter strains.<\/p>\n\n\n\n<p>The new species <em>Methanobrevibacter intestini<\/em> WWM1085 differs genetically and physiologically from all previously known species. It thrives exclusively under strictly anaerobic conditions, produces methane, and might be associated with inflammatory processes in the human body. The second strain discovered, a variant of <em>Methanobrevibacter smithii<\/em> called \u201cGRAZ-2\u201d, also shows unusual characteristics: It produces formate (formic acid), a molecule that can interfere with the energy metabolism of other microorganisms in the gut.<\/p>\n\n\n\n<p>This work, published in the International Journal of Systematic and Evolutionary Microbiology, shows that the world of archaea in the human gut is more complex and relevant than previously assumed, and offers enormous potential for further research into health and disease.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-custom-neon-purple-background-color has-background wp-element-button\" href=\"https:\/\/www.microbiologyresearch.org\/content\/journal\/ijsem\/10.1099\/ijsem.0.006751\" target=\"_blank\" rel=\"noreferrer noopener\">Link to publication<\/a><\/div>\n\n\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-custom-neon-purple-background-color has-background wp-element-button\" href=\"https:\/\/www.medunigraz.at\/news\/detail\/neue-spezies-im-menschlichen-darm-entdeckt\" target=\"_blank\" rel=\"noreferrer noopener\">Press Release MedUni Graz (in German)<\/a><\/div>\n\n\n\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-custom-neon-purple-background-color has-background wp-element-button\" href=\"https:\/\/www.microplanet.at\/wp-content\/uploads\/2024\/09\/Biosketch-Moissl-Eichinger.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">Christine&#8217;s Biosketch<\/a><\/div>\n<\/div>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>CoE researchers from the Medical University of Graz, along with colleagues from Germany and the US, have isolated two strains of Methanobrevibacter from the human intestine.<\/p>\n","protected":false},"author":16,"featured_media":4768,"comment_status":"open","ping_status":"open","sticky":false,"template":"wp-custom-template-news-post-without-featured-image","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-4762","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/posts\/4762","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/users\/16"}],"replies":[{"embeddable":true,"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/comments?post=4762"}],"version-history":[{"count":12,"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/posts\/4762\/revisions"}],"predecessor-version":[{"id":4807,"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/posts\/4762\/revisions\/4807"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/media\/4768"}],"wp:attachment":[{"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/media?parent=4762"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/categories?post=4762"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/tags?post=4762"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}