{"id":5305,"date":"2025-06-13T13:26:50","date_gmt":"2025-06-13T12:26:50","guid":{"rendered":"https:\/\/www.microplanet.at\/?p=5305"},"modified":"2025-06-13T13:27:53","modified_gmt":"2025-06-13T12:27:53","slug":"new-coe-publication-presents-a-milestone-for-archaeal-microbiology","status":"publish","type":"post","link":"https:\/\/www.microplanet.at\/index.php\/news\/new-coe-publication-presents-a-milestone-for-archaeal-microbiology\/","title":{"rendered":"New CoE Publication presents a milestone for archaeal microbiology"},"content":{"rendered":"\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"985\" src=\"https:\/\/www.microplanet.at\/wp-content\/uploads\/2025\/06\/Weinberger1-1024x985.jpg\" alt=\"\" class=\"wp-image-5314\" srcset=\"https:\/\/www.microplanet.at\/wp-content\/uploads\/2025\/06\/Weinberger1-1024x985.jpg 1024w, https:\/\/www.microplanet.at\/wp-content\/uploads\/2025\/06\/Weinberger1-300x289.jpg 300w, https:\/\/www.microplanet.at\/wp-content\/uploads\/2025\/06\/Weinberger1-768x739.jpg 768w, https:\/\/www.microplanet.at\/wp-content\/uploads\/2025\/06\/Weinberger1-1536x1478.jpg 1536w, https:\/\/www.microplanet.at\/wp-content\/uploads\/2025\/06\/Weinberger1.jpg 2000w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p class=\"has-small-font-size\" style=\"font-style:normal;font-weight:300\"><strong>a, e, i, l<\/strong> Scanning electron micrographs of whole cells showing potential vesicle development on their cell surface. <strong>b, f, g, j, k <\/strong>Ultra-thin transmission electron micrographs of whole cells, highlighting vesicles located inside or attached to the cells. <strong>c, d, h, m<\/strong> Transmission electron micrographs of isolated vesicles. Arrows indicate the presence of archaeal extracellular vesicles (AEVs).<\/p>\n\n\n\n<p>Viktoria Weinberger and colleagues from the lab of CoE Deputy Director of Research Christine Moissl-Eichinger from the Medical University of Graz explored the fascinating world of extracellular vesicles (EVs) produced by human gut archaea.<\/p>\n\n\n\n<p>They analyzed EVs from multiple methanogenic strains (Methanobrevibacter smithii, M. intestini, and Methanosphaera stadtmanae) and found adhesin-like proteins and immunomodulatory metabolites that elicited strain-specific immune responses in vitro. A parallel study by Baquero et al. published in the same issue revealed that EVs from M. smithii carry extrachromosomal circular DNA (eccDNA) and histone-enriched cargo, suggesting novel roles in gene transfer and methanogenesis regulation.<\/p>\n\n\n\n<p>These findings underscore the importance of extracellular vesicles in archaeal biology and open exciting research directions in host-microbe interaction and gut ecosystem dynamics.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link has-custom-neon-purple-background-color has-background wp-element-button\" href=\"https:\/\/www.nature.com\/articles\/s41467-025-60271-w\" target=\"_blank\" rel=\"noreferrer noopener\">Link to publication<\/a><\/div>\n<\/div>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A study on extracellular vesicles of archaea from the lab of Deputy Director of Research Christine Moissl-Eichinger was published in Nature Communications.<\/p>\n","protected":false},"author":16,"featured_media":5308,"comment_status":"open","ping_status":"open","sticky":false,"template":"wp-custom-template-news-post-without-featured-image","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-5305","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/posts\/5305","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/users\/16"}],"replies":[{"embeddable":true,"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/comments?post=5305"}],"version-history":[{"count":6,"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/posts\/5305\/revisions"}],"predecessor-version":[{"id":5332,"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/posts\/5305\/revisions\/5332"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/media\/5308"}],"wp:attachment":[{"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/media?parent=5305"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/categories?post=5305"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.microplanet.at\/index.php\/wp-json\/wp\/v2\/tags?post=5305"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}